Clonal hematopoiesis

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Clonal Hematopoiesis

Clonal hematopoiesis (pronounced: kloh-nal he-muh-toh-poy-ee-sis) is a medical condition that involves the abnormal growth of blood cells. The term is derived from the Greek words "klonos" (meaning twig) and "haima" (meaning blood), referring to the branching growth of blood cells.

Definition

Clonal hematopoiesis is a condition where a single blood stem cell, or a clone of such cells, begins to dominate in the production of blood cells. This can lead to a variety of health issues, including anemia, leukemia, and other blood disorders.

Causes

The exact cause of clonal hematopoiesis is not fully understood. However, it is believed to be associated with aging and genetic mutations. Certain genetic mutations such as DNMT3A, TET2, and ASXL1 are often found in individuals with clonal hematopoiesis.

Symptoms

Clonal hematopoiesis often does not present any symptoms and is usually discovered during routine blood tests. However, in some cases, it can lead to symptoms associated with other blood disorders, such as fatigue, weakness, and increased susceptibility to infections.

Treatment

Treatment for clonal hematopoiesis is typically focused on managing the symptoms and preventing complications. This may involve regular monitoring, medication, and in some cases, stem cell transplantation.

Related Terms

External links

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