Clonazepam
Contents
- 1 Information about Clonazepam
- 2 Liver safety of Clonazepam
- 3 Mechanism of action of Clonazepam
- 4 FDA approval information for Clonazepam
- 5 Clinical use of Clonazepam
- 6 Dosage and administration for Clonazepam
- 7 Side effects of Clonazepam
- 8 Cost and Coupons - Clonazepam
- 9 Reviews for Clonazepam
- 10 Articles on Clonazepam
- 11 Learn more about Clonazepam
Information about Clonazepam
Clonazepam is a benzodiazepine used predominantly as an anticonvulsant as adjunctive therapy in management of epilepsy.
Liver safety of Clonazepam
Therapy with clonazepam is not associated with serum aminotransferase elevations, and clinically apparent liver injury from clonazepam, if it occurs at all, must be exceedingly rare.
Mechanism of action of Clonazepam
Clonazepam (kloe naz' e pam) is a benzodiazepine with particularly potent activity against spread of seizure activity in several animal models. The antiseizure activity of the benzodiazepines is mediated by their ability to enhance gamma-aminobutyric acid (GABA) mediated inhibition of synaptic transmission through binding to the GABA A receptor.
FDA approval information for Clonazepam
Clonazepam was approved in the United States for treatment of epilepsy in 1997 and currently more than 20 million prescriptions are filled yearly.
Clinical use of Clonazepam
Clonazepam is currently indicated for management of absence seizures and myoclonic seizures in children as well as generalized seizure disorders in both adults and children. Clonazepam is effective in status epilepticus, but diazepam and lorazepam are preferable because of their longer half lives. Clonazepam is also used for restless leg syndrome, dysarthria, tic disorders, panic disorder and acute mania.
Dosage and administration for Clonazepam
Clonazepam is available in generic forms and under the brand name Klonopin in tablets of 0.5, 1.0 and 2 mg as well as in orally disintegrating tablets for pediatric use. The recommended initial dose for adults is 1.5 mg daily in three divided doses, increasing as needed to a maximum dose of 20 mg daily.
Side effects of Clonazepam
The most common side effects of clonazepam are dose related and include drowsiness, lethargy, ataxia, dysarthria and dizziness. Tolerance develops to these side effects, but tolerance may also develop to the antiseizure effects. Anticonvulsants
Cost and Coupons - Clonazepam
- GoodRx compare cost & coupons for Clonazepam
- Find the lowest cost of Clonazepam
- Search for Coupons for Clonazepam
Reviews for Clonazepam
Articles on Clonazepam
This article is a stub. YOU can help Wikimd by expanding it!
Learn more about Clonazepam
|
| ||
|
Articles |
Policies / Guidelines | Social Media |
|---|---|---|
 | ||
|
Media |
Patient Resources / Community |  |
  | ||
|
Evidence Based Medicine |
Healthcare Provider Resources |  |
 | ||
|
Clinical Trials |
News |  |
    | ||
| External:W8MD Weight Loss, Sleep & MedSpa | Wellness Topics A-Z | Other resources |
|
|
||
Ad. Tired of being overweight? W8MD's insurance weight loss* program can HELP | Advertise on WikiMD |
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer. * Individual results may vary.
