doctor


W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
28,711 pages, 4,106,544 edits & 35,503,318 views.

Free unbiased diet, health and wellness info!

Clopidogrel

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

Information about Clopidogrel/en

Clopidogrel is an inhibitor of platelet aggregation that is used to decrease the risk of myocardial infarction and stroke in patients known to have atherosclerosis. 

Liver safety of Clopidogrel/en

Clopidogrel has been linked to rare instances of idiosyncratic, clinically apparent acute liver injury.

Mechanism of action of Clopidogrel/en

Clopidogrel (kloe pid' oh grel) is an inhibitor of adenosine diphosphate (ADP)-induced platelet aggregation and is used widely to decrease the risk of myocardial infarction and stoke in patients who have documented coronary or cerebrovascular disease or previous heart attack or stroke.  Activated platelets release ADP which binds to platelet receptors, causing activation of intracellular glycoprotein IIb/IIIA complex which triggers platelet adherence and aggregation.  The aggregation of platelets plays an important role in the growth of atheromatous plaques, which can lead to coronary, cerebral and peripheral arterial occlusions.  In large clinical trials, clopidogrel therapy has been shown to decrease the frequency of recurrence of myocardial infarction and stroke. 

FDA approval information for Clopidogrel/en

Clopidogrel was approved for use in the United States in 1997 and is widely used, with more than 1.5 million prescriptions filled yearly. 

Clinical use of Clopidogrel/en

Current indications include reduction of atherosclerotic events (myocardial infarction, stroke, vascular death) in patients with documented atherosclerosis and in patients with acute myocardial infarction or unstable angina. 

Dosage and administration for Clopidogrel/en

Clopidogrel is available in 75 mg tablets generically and under the brand name of Plavix.  The usual dose is 75 mg daily, sometimes with a loading dose of 300 mg on day one. 

Side effects of Clopidogrel/en

Side effects are not common, but can include headache, dizziness, fatigue, gastrointestinal upset, nausea, arthralgias and rash.

Cost and Coupons - Clopidogrel/en

Reviews for Clopidogrel/en

Learn more about Clopidogrel/en

Latest research (Pubmed)

PubMed
Wikipedia

External links


edit 

WikiMD needs you!

This WikiMD article Clopidogrel/en is a stub.
If you are a healthcare professional familiar with the topic Clopidogrel/en, or
A subject matter expert or authority on Clopidogrel/en, you can help us.
About | Mission | Paid editors welcome!

Clopidogrel/en is part of WikiMD's Physician reviewed^ articles available 4free, 4all, 4ever!
Medicine: Health - Encyclopedia‏‎‏‎ - Topics‏‎ -‏‎ Diseases‏‎ - Cancer - Rare diseases - Random Page Navigation: Drugs - Wellness - Obesity‏‎ - Diet - Ketogenic diet - W8MD weight loss diet - Editors: Recently Edited Pages - Alphabetical Order - Sponsors - USMLE The content on or accessible through WikiMD is for informational purposes only. WikiMD is not a substitute for professional medical advice. ^See full Disclaimers
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP*
Special: W8MD's tele-weight loss consultations only $99.99. Call 718-946-5500. Limited acceptance.

Other languages: