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Cmv pp65 peptide
- a peptide derived from cytomegalovirus (cmv) internal matrix protein pp65. Cmv pp65 peptide antigen is used in recombinant vaccinia virus as an hla a restricted epitope to produce vaccines and specific cd8+ and cd4+ cell responses against cmv infection, a serious complication of allogeneic bone marrow transplantation (bmt). In bmt, cmv infection may be prevented by passive immunization with donor derived cmv pp65 specific t cell clones if provided early post bmt.
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