Coagulation factors
Coagulation Factors
Coagulation factors (/koʊˌæɡjʊˈleɪʃən ˈfæktərz/) are a group of proteins in the blood that work together to make the blood clot. They are part of the coagulation cascade, a complex process that stops bleeding when blood vessels are injured.
Etymology
The term "coagulation" comes from the Latin word "coagulare," which means "to curdle." "Factor" is derived from the Latin "facere," meaning "to make" or "to do."
Coagulation Factors
There are thirteen identified coagulation factors, each designated by a Roman numeral. They include:
- Factor I (Fibrinogen)
- Factor II (Prothrombin)
- Factor III (Tissue Factor)
- Factor IV (Calcium)
- Factor V (Proaccelerin)
- Factor VII (Proconvertin)
- Factor VIII (Antihemophilic factor)
- Factor IX (Christmas factor)
- Factor X (Stuart-Prower factor)
- Factor XI (Plasma Thromboplastin Antecedent)
- Factor XII (Hageman factor)
- Factor XIII (Fibrin-stabilizing factor)
Each factor plays a unique role in the coagulation cascade, and deficiencies in any of these factors can lead to bleeding disorders such as hemophilia and Von Willebrand disease.
Related Terms
- Hemostasis: The process of stopping bleeding.
- Thrombosis: The formation of a blood clot inside a blood vessel.
- Anticoagulant: A substance that prevents coagulation.
- Fibrinolysis: The process of breaking down fibrin, the main protein component of blood clots.
External links
- Medical encyclopedia article on Coagulation factors
- Wikipedia's article - Coagulation factors
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