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Collagen gene

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 - collagen genes encode different forms of collagen, the principle fibrous protein of connective tissue, all consisting of triple helix alpha polypeptide chains. Collagen is differentiated from other fibrous proteins by its content of proline, hydroxyproline, and hydroxylysine; by its absence of tryptophan; and by its high content of polar groups. Hydroxyproline residues likely promote the triple helical fibrous structure of collagen. (nci)

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