Collagenous colitis

Collagenous colitis is a medical condition characterized by chronic, watery diarrhea. The term "collagenous" refers to the thick layer of protein (collagen) that develops in the tissue of the colon.

Pronunciation

Collagenous colitis is pronounced as kuh-LAJ-uh-nus koh-LY-tis.

Etymology

The term "collagenous colitis" is derived from the Greek words "kolla" meaning glue and "gen" meaning producing, referring to the collagen layer, and "colitis" from the Greek "kolon" meaning colon and "-itis" meaning inflammation.

Symptoms

The primary symptom of collagenous colitis is chronic, non-bloody, watery diarrhea. Other symptoms may include abdominal pain, weight loss, and mild cramping.

Causes

The exact cause of collagenous colitis is unknown. However, it is believed to be associated with autoimmune disorders, such as rheumatoid arthritis, lupus, and celiac disease. Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), may also contribute to the development of this condition.

Diagnosis

Diagnosis of collagenous colitis is typically made through a colonoscopy with biopsy. The biopsy will show a thickened layer of collagen in the tissue of the colon.

Treatment

Treatment for collagenous colitis may include medications to control diarrhea, such as bismuth subsalicylate or loperamide. In some cases, corticosteroids may be used to reduce inflammation.

Related Terms

• Microscopic colitis
• Lymphocytic colitis
• Inflammatory bowel disease
• Autoimmune disease

External links

• Medical encyclopedia article on Collagenous colitis
• Wikipedia's article - Collagenous colitis

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