Comby sign

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Comby Sign

Comby Sign (/ˈkɒmbi/; from French, named after the French pediatrician Jacques Jean Léonce Comby) is a clinical sign in medicine that is used to diagnose measles. It is characterized by the presence of small, white spots on the buccal mucosa opposite the lower molars, which appear before the onset of the measles rash.

Etymology

The term "Comby Sign" is named after Jacques Jean Léonce Comby, a French pediatrician who first described this sign in the late 19th century. Comby was known for his extensive work in pediatric medicine, particularly in the field of infectious diseases.

Clinical Significance

Comby Sign is a significant clinical sign in the diagnosis of measles, a highly contagious viral disease. The presence of these white spots, also known as Koplik's spots, is one of the earliest signs of measles infection. They typically appear 1-2 days before the onset of the measles rash and can be a useful diagnostic tool in the early stages of the disease.

Related Terms

  • Measles: A highly contagious viral disease characterized by fever, cough, conjunctivitis, and a characteristic rash.
  • Koplik's spots: Small, white spots on the buccal mucosa, which are an early sign of measles infection.
  • Buccal mucosa: The inner lining of the cheeks and lips, which is where Koplik's spots appear in measles infection.

See Also

External links

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