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Complement component gene

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Complement component gene - these genes encode more than 30 proteins of the complement system engaged in host defense. This system provides both an independent immune system capable of attacking microbes as well as other foreign material and an adjunct to the antibody system. Once activated, the complement system fires in a cascade like fashion in which one component activates the next. Both swift and powerful, millions of complement components can deposit on an invading microbe within only a few minutes. Such a potent system requires strict regulation to avoid host injury. Membrane cofactor protein (mcp) is one critical regulator aimed at controlling inadvertent complement activation on host cells and nearly every cell examined expresses mcp on its cell membrane.

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Complement component gene for any updates.

 

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