W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
15,609 pages, 4,131,492 edits & 37,452,872 views.

Free unbiased diet, health and wellness info!

Compound Kushen injection

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

Definition

It is a traditional Chinese medicine (TCM) formulation.

Composition

It is composed of compound Kushen injection (CKI) containing aqueous extracts from the roots of Kushen (Radix Sophorae Flavescentis) and Baituling (Rhizoma Smilacis Glabrae), with potential antineoplastic and immunomodulating activities.

Ingredients

CKI contains numerous chemicals including alkaloids, such as matrine and oxymatrine, flavonoids, alkylxanthones, quinones, triterpene glycosides, fatty acids, and essential oils.

Mechanism of action

Although the exact mechanism(s) of action through which CKI exerts its effects has yet to be fully elucidated, CKI is able to interfere with the activation of various signal transduction pathways, such as the Wnt/beta-catenin signaling pathway, inhibit nuclear factor-kappa B (NF-κB) activation, and block the activity of multiple receptor tyrosine kinases, such as epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR).

Tumor cell apoptosis

CKI induces apoptosis in and inhibits proliferation, migration, invasion and adhesion of tumor cells. CKI also modulates the production of inflammatory mediators.

Learn more about Compound Kushen injection

Latest research - Compound Kushen injection

PubMed
Clinical trials

External links

Wikipedia
Medicine icon
Medicine icon

This WikiMD article Compound Kushen injection is a stub. If you are familiar with the topic Compound Kushen injection, you can help us. Paid editors welcome!

 

Compound Kushen injection is part of WikiMD's free ^articles!

^Compound Kushen injection (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available