W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
15,602 pages, 4,131,460 edits & 37,452,872 views.

Free unbiased diet, health and wellness info!

Conformation dependent mutation detection

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

Conformation dependent mutation detection - polymorphism, single stranded conformational, detection. Altered migration of single stranded dna molecules in non denaturing gels based upon 3 d conformation. Uses pcr and/or restriction enzymes to generate short dsdna molecules spanning a sequence of interest. The dsdna molecules are heat denatured, and then quickly cooled. Each ssdna molecule will assume a secondary structure (conformation) dependent upon its unique sequence. Base mutations will often result in altered conformations, with altered mobilities, which can be visualized following separation in non denaturing gels. (nci/osp)

Up to date info


Latest research - Conformation dependent mutation detection

Clinical trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Conformation dependent mutation detection for any updates.


Conformation dependent mutation detection is part of WikiMD's free ^articles!

^Conformation dependent mutation detection (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available