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Conium

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(ko-ne f -um) [kwvswv, hemlock]. Hem- lock. Both the leaves and the fruit are official in the B. P. The conium of the U. S. P. is the full-grown but unripe fruit of the spotted hemlock, C. maculatum. It contains three alkaloids and a volatile oil. Its properties are mainly due to the alkaloids conin, C 8 H 15 N, and methylconin, C 8 H 34 NCH 3 . It produces motor paralysis, without loss of sensation or of consciousness. Toxic doses cause death by paralysis of the organs of respiration. It is valuable in acute mania, delirium tremens, tetanus, blepharospasm, asthma, and whoop- ing-cough. Conii, Abstractum, made from conium, 200; dilute hydrochloric acid, 6; sugar of milk and alcohol, q. s. to make too parts of abstract. Dose §-3 gr. (0.032- 0.2 Gm.). Conii, Cataplasma (B. P.), made from the leaves; for external use. Conii, Fluid extractum (U. S. P.). Dose 1-2 min. (0.065-0.13 Cc). Conii, Pilula, Composita (B. P.), contains extract of hemlock and ipecac. Dose 5-10 gr. (0.32-0.65 Gm.). Conii, Suc- cus (B. P.), made from the leaves. Dose 30 min.-2 dr. (2-8 Cc). Conii, Tinctura, 15 % strength. Dose 10 min.-i dr. (0.65-4.0

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