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Connective-tissue disease (Collagen disease)

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 -- Any one of many abnormal conditions characterized by diffuse immunologic and inflammatory changes in small blood vessels and connective tissue. Some collagen diseases include systemic lupus erythematosus, scleroderma, polymyositis and rheumatic fever. See Lupus erythematosus, systemic; scleroderma; polymyositis; rheumatic fever.

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