Coronary flow reserve
Coronary Flow Reserve
The Coronary Flow Reserve (CFR) (pronunciation: kuh-ROH-nuh-ree flow reh-ZURV) is a term used in Cardiology to describe the maximum increase in blood flow through the Coronary arteries above the normal resting volume.
Etymology
The term is derived from the Latin coronarius meaning "crown" or "garland", and the English flow reserve referring to the capacity for increased flow.
Definition
The Coronary Flow Reserve is the ratio of maximum flow (during stress) to resting flow in the coronary arteries. It is a useful measure of the functional capacity of the coronary circulation and is used to assess the presence and severity of Coronary artery disease.
Measurement
CFR can be measured using various techniques including Doppler echocardiography, Cardiac magnetic resonance imaging (MRI), and Positron emission tomography (PET). These techniques allow for non-invasive assessment of the coronary flow reserve.
Clinical Significance
CFR is a significant predictor of cardiovascular events in patients with coronary artery disease. A reduced CFR indicates impaired coronary vasodilator capacity, which is associated with a higher risk of Myocardial infarction (heart attack) and Cardiac death.
Related Terms
- Coronary artery disease
- Doppler echocardiography
- Cardiac magnetic resonance imaging
- Positron emission tomography
- Myocardial infarction
- Cardiac death
External links
- Medical encyclopedia article on Coronary flow reserve
- Wikipedia's article - Coronary flow reserve
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