Corynanthine
Corynanthine
Corynanthine, also known as rauhimbine, is an alkaloid found in certain species of the plant genus Rauvolfia. It is chemically related to the yohimbine and reserpine alkaloids. Pronounced as "kor-ee-nan-theen", the term is derived from the genus name Corynanthe, a related plant genus from which the compound was first isolated.
Description
Corynanthine is a type of indole alkaloid, a large class of alkaloids that are derived from the amino acid tryptophan. It is a stereoisomer of yohimbine, meaning it has the same molecular formula but a different three-dimensional structure. Corynanthine acts as an antagonist at alpha-1 adrenergic receptors and alpha-2 adrenergic receptors, which are types of protein molecules that respond to adrenaline and noradrenaline in the body.
Medical Uses
Corynanthine has been studied for its potential use in the treatment of various medical conditions. Due to its ability to block alpha-1 and alpha-2 adrenergic receptors, it may have applications in treating conditions such as hypertension and certain types of sexual dysfunction. However, more research is needed to fully understand the potential benefits and risks of corynanthine in medical treatment.
Related Terms
- Alkaloid
- Rauvolfia
- Yohimbine
- Reserpine
- Indole alkaloid
- Tryptophan
- Stereoisomer
- Antagonist
- Alpha-1 adrenergic receptor
- Alpha-2 adrenergic receptor
- Adrenaline
- Noradrenaline
- Hypertension
- Sexual dysfunction
External links
- Medical encyclopedia article on Corynanthine
- Wikipedia's article - Corynanthine
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