DT-PACE

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DT-PACE is a chemotherapy regimen used in the treatment of multiple myeloma. It is an acronym for the drugs used in the regimen: Dexamethasone, Thalidomide, Cisplatin (or Platinol), Adriamycin (or Doxorubicin), Cyclophosphamide, and Etoposide.

Pronunciation

DT-PACE: /diː tiː peɪs/

Etymology

The term DT-PACE is an acronym derived from the names of the drugs used in the regimen.

Chemotherapy Regimen

Chemotherapy is a type of cancer treatment that uses drugs to kill cancer cells. DT-PACE is a specific regimen that includes several drugs, each with a different role:

  • Dexamethasone is a corticosteroid that reduces inflammation and suppresses the immune system.
  • Thalidomide is an immunomodulatory drug that inhibits the growth of new blood vessels, thereby starving the cancer cells.
  • Cisplatin (or Platinol) is a platinum-containing drug that interferes with the DNA in cancer cells, preventing them from dividing and growing.
  • Adriamycin (or Doxorubicin) is an anthracycline antibiotic that interferes with the DNA in cancer cells, preventing them from dividing and growing.
  • Cyclophosphamide is an alkylating agent that damages the DNA in cancer cells, preventing them from dividing and growing.
  • Etoposide is a topoisomerase inhibitor that interferes with the DNA in cancer cells, preventing them from dividing and growing.

Related Terms

  • Multiple Myeloma: A type of blood cancer that DT-PACE is often used to treat.
  • Chemotherapy: The type of cancer treatment that DT-PACE is a part of.
  • Cancer: The general term for diseases characterized by abnormal cell growth.

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