Dabrafenib

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Dabrafenib

Dabrafenib (pronounced da-bra-fe-nib) is a medication used in the treatment of certain types of cancer, specifically melanoma that is BRAF mutation-positive.

Etymology

The name "Dabrafenib" is derived from the gene it targets, BRAF, and the class of drugs it belongs to, known as kinase inhibitors.

Usage

Dabrafenib is used to treat melanoma, a type of skin cancer, that cannot be removed by surgery or is in a late stage. It is also used to treat lung cancer that is BRAF V600 mutation-positive. Dabrafenib works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.

Side Effects

Common side effects of Dabrafenib include fever, fatigue, nausea, headache, joint pain, rash, and hair loss. Serious side effects can include skin cancer, high blood pressure, bleeding problems, and heart problems.

Related Terms

  • BRAF: A gene that provides instructions for making a protein that helps transmit signals within cells (a kinase).
  • Melanoma: A type of skin cancer that begins in cells known as melanocytes.
  • Kinase inhibitors: A type of drug that blocks certain proteins called kinases.
  • Lung cancer: A type of cancer that begins in the lungs.

External links

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