Diffuse proliferative nephritis
Diffuse proliferative nephritis (pronunciation: dih-fyoos proh-lih-feh-rah-tiv neh-fry-tis) is a type of glomerulonephritis, a group of diseases that cause inflammation and damage to the kidney's filtering units, known as the glomeruli.
Etymology
The term "diffuse proliferative nephritis" is derived from the Latin word "diffusus", meaning "spread out", the Latin word "proliferare", meaning "to reproduce", and the Greek word "nephros", meaning "kidney". The term "itis" is a common suffix in medical terminology that indicates inflammation.
Definition
Diffuse proliferative nephritis is a severe form of glomerulonephritis. It is characterized by widespread proliferation of cells (diffuse) in the glomeruli, leading to significant inflammation and damage. This condition is often associated with systemic diseases, such as lupus, that affect multiple organs and systems in the body.
Symptoms
Symptoms of diffuse proliferative nephritis may include hematuria (blood in the urine), proteinuria (excessive protein in the urine), edema (swelling), and hypertension (high blood pressure).
Diagnosis
Diagnosis of diffuse proliferative nephritis typically involves a combination of blood tests, urine tests, and a kidney biopsy. The biopsy, which involves taking a small sample of kidney tissue for examination under a microscope, can help confirm the diagnosis and determine the extent of kidney damage.
Treatment
Treatment for diffuse proliferative nephritis typically involves medications to reduce inflammation and suppress the immune system, such as corticosteroids and immunosuppressive drugs. In severe cases, dialysis or a kidney transplant may be necessary.
See also
External links
- Medical encyclopedia article on Diffuse proliferative nephritis
- Wikipedia's article - Diffuse proliferative nephritis
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