Digoxin toxicity

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Digoxin Toxicity

Digoxin toxicity (pronunciation: dij-ox-in tox-ic-ity), also known as Digitalis toxicity, is a medical condition that occurs when the level of digoxin, a medication used to treat various heart conditions, becomes too high in the body.

Etymology

The term "Digoxin" is derived from Digitalis lanata, the plant species from which the drug is extracted. The term "toxicity" comes from the Greek word "toxikon," which means "poison for arrows."

Symptoms

Symptoms of digoxin toxicity can range from mild to severe and may include nausea, vomiting, diarrhea, abdominal pain, confusion, hallucinations, blurred vision, yellow-green vision, and arrhythmias (irregular heart rhythms).

Causes

Digoxin toxicity can occur from an overdose of digoxin or from the accumulation of digoxin in the body over time. Factors that increase the risk of digoxin toxicity include advanced age, kidney disease, and certain drug interactions.

Diagnosis

Diagnosis of digoxin toxicity is based on clinical symptoms and laboratory tests. A blood test can measure the level of digoxin in the body. An electrocardiogram (ECG) can detect arrhythmias caused by digoxin toxicity.

Treatment

Treatment for digoxin toxicity includes discontinuing the drug, treating the symptoms, and in severe cases, administering digoxin immune fab, an antidote that binds to digoxin and removes it from the body.

Related Terms

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