Dimethisterone
Dimethisterone
Dimethisterone (pronounced as di-meth-is-ter-one) is a progestin medication which was previously used in hormone therapy but is now rarely used. It is a derivative of testosterone and is related to other testosterone-derived progestins like ethisterone and noretynodrel.
Etymology
The term "Dimethisterone" is derived from the chemical structure of the compound. The prefix "di-" refers to the presence of two methyl groups, "-eth-" refers to the ethyl group, and "-sterone" is a common suffix used in the nomenclature of steroids, indicating a ketone group at the 17-position.
Usage
Dimethisterone was used in the treatment of gynecological disorders such as menstrual disorders, endometriosis, and to prevent threatened miscarriage. It was also used in combination with an estrogen as a component of menopausal hormone therapy to prevent endometrial hyperplasia and uterine cancer.
Pharmacology
Dimethisterone is a synthetic progestogen, meaning it mimics the effects of the natural hormone progesterone. It binds to and activates the progesterone receptor, exerting its effects in the body.
Related Terms
- Progestin: A type of medication which is used mainly in hormonal birth control and menopausal hormone therapy.
- Testosterone: The primary male sex hormone and an anabolic steroid.
- Ethisterone: A progestin medication which was used to treat gynecological disorders.
- Noretynodrel: A progestin medication which was used in some of the first oral contraceptives.
External links
- Medical encyclopedia article on Dimethisterone
- Wikipedia's article - Dimethisterone
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