Dyskeratosis
Dyskeratosis
Dyskeratosis (pronounced dis-ker-uh-TOH-sis) is a medical term referring to an abnormality in the process of keratinization, which is the formation of keratin, a protein that strengthens the skin, hair, and nails.
Etymology
The term "dyskeratosis" is derived from the Greek words "dys" meaning "bad" or "difficult", "kerato" meaning "horny" or "cornea", and "osis" meaning "condition". Thus, it refers to a condition characterized by abnormal keratin formation.
Definition
Dyskeratosis is a condition characterized by the abnormal development of skin cells, leading to changes in the skin, nails, and mucous membranes. It is often associated with a group of rare genetic disorders known as Dyskeratosis Congenita.
Symptoms
Symptoms of dyskeratosis may include skin pigmentation, nail dystrophy, and oral leukoplakia. Other symptoms may include bone marrow failure, pulmonary fibrosis, and an increased risk of cancer.
Related Terms
- Keratinization: The process by which keratin, a protein, is produced in cells.
- Dyskeratosis Congenita: A rare genetic disorder characterized by abnormal skin pigmentation, nail dystrophy, and mucosal leukoplakia.
- Leukoplakia: A condition characterized by white patches on the mucous membranes, often associated with dyskeratosis.
- Pulmonary Fibrosis: A lung disease that occurs when lung tissue becomes damaged and scarred, often a symptom of dyskeratosis.
See Also
External links
- Medical encyclopedia article on Dyskeratosis
- Wikipedia's article - Dyskeratosis
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