Ecthyma gangrenosum
Ecthyma Gangrenosum
Ecthyma gangrenosum (pronunciation: ek-thy-ma gang-re-no-sum) is a rare, severe skin condition often associated with Pseudomonas aeruginosa infection, particularly in immunocompromised individuals.
Etymology
The term "ecthyma" originates from the Greek word "ekthyma", meaning "pustule", while "gangrenosum" is derived from the Latin "gangraena", referring to "gangrene" or tissue death.
Definition
Ecthyma gangrenosum is characterized by the rapid progression of necrotic skin lesions, typically presenting as small, red, painful nodules or pustules that quickly evolve into larger ulcers with black necrotic centers. These lesions are most commonly found on the buttocks, extremities, and perineum, but can occur anywhere on the body.
Causes
The primary cause of ecthyma gangrenosum is Pseudomonas aeruginosa, a gram-negative bacterium. However, it can also be caused by other bacteria, including Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae. The condition is most common in individuals with weakened immune systems, such as those with neutropenia, HIV/AIDS, or undergoing chemotherapy.
Diagnosis
Diagnosis of ecthyma gangrenosum is typically made based on the characteristic appearance of the skin lesions. Laboratory tests, including blood cultures and skin biopsy, may be used to confirm the diagnosis and identify the causative organism.
Treatment
Treatment of ecthyma gangrenosum involves aggressive antibiotic therapy to treat the underlying infection. Surgical debridement of necrotic tissue may also be necessary. In severe cases, hospitalization and intensive care may be required.
Related Terms
External links
- Medical encyclopedia article on Ecthyma gangrenosum
- Wikipedia's article - Ecthyma gangrenosum
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