Elbasvir and grazoprevir
Elbasvir and Grazoprevir
Elbasvir (/ɛlˈbæsvɪər/) and Grazoprevir (/ɡræˈzoʊprɛvɪər/) are antiviral medications used in the treatment of Hepatitis C. They are often used in combination for the treatment of chronic hepatitis C virus (HCV) genotypes 1 and 4.
Etymology
The name "Elbasvir" is derived from the names of the scientists who first synthesized it. "Grazoprevir" is a combination of "graz" from "graziano", meaning grace in Italian, and "previr" from "prevention" and "virus".
Pharmacology
Elbasvir is a NS5A inhibitor, which means it blocks a specific protein that the hepatitis C virus needs to replicate. Grazoprevir is a NS3/4A protease inhibitor, which also blocks a protein needed by the virus to reproduce.
Usage
Elbasvir and Grazoprevir are used together in a single pill, taken once daily. This combination therapy is typically prescribed for a 12-week course, but may be extended to 16 weeks for some patients.
Side Effects
Common side effects of Elbasvir and Grazoprevir include fatigue, headache, and nausea. More serious side effects can include liver problems and reactivation of hepatitis B in those who have previously been infected with this virus.
Related Terms
See Also
External links
- Medical encyclopedia article on Elbasvir and grazoprevir
- Wikipedia's article - Elbasvir and grazoprevir
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