Elbasvir and grazoprevir

From WikiMD.org
Jump to navigation Jump to search

Elbasvir and Grazoprevir

Elbasvir (/ɛlˈbæsvɪər/) and Grazoprevir (/ɡræˈzoʊprɛvɪər/) are antiviral medications used in the treatment of Hepatitis C. They are often used in combination for the treatment of chronic hepatitis C virus (HCV) genotypes 1 and 4.

Etymology

The name "Elbasvir" is derived from the names of the scientists who first synthesized it. "Grazoprevir" is a combination of "graz" from "graziano", meaning grace in Italian, and "previr" from "prevention" and "virus".

Pharmacology

Elbasvir is a NS5A inhibitor, which means it blocks a specific protein that the hepatitis C virus needs to replicate. Grazoprevir is a NS3/4A protease inhibitor, which also blocks a protein needed by the virus to reproduce.

Usage

Elbasvir and Grazoprevir are used together in a single pill, taken once daily. This combination therapy is typically prescribed for a 12-week course, but may be extended to 16 weeks for some patients.

Side Effects

Common side effects of Elbasvir and Grazoprevir include fatigue, headache, and nausea. More serious side effects can include liver problems and reactivation of hepatitis B in those who have previously been infected with this virus.

Related Terms

See Also

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski