Elsamitrucin

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Elsamitrucin

Elsamitrucin (pronunciation: el-sa-mi-tru-cin) is a chemotherapeutic agent used in the treatment of various types of cancer. It is a semi-synthetic derivative of the natural compound Elsamicin A, which is isolated from the bacterium Actinomycete.

Etymology

The term "Elsamitrucin" is derived from the name of its parent compound, Elsamicin A. The suffix "-trucin" is commonly used in the nomenclature of chemotherapeutic agents.

Usage

Elsamitrucin is primarily used in the treatment of leukemia, lymphoma, and certain solid tumors. It works by inhibiting the growth of cancer cells and eventually causing their death.

Mechanism of Action

Elsamitrucin exerts its anti-cancer effects by binding to the DNA of cancer cells and inhibiting the enzyme topoisomerase II, which is essential for DNA replication and cell division. This leads to DNA damage and cell death.

Side Effects

Common side effects of Elsamitrucin include nausea, vomiting, hair loss, and fatigue. More serious side effects can include bone marrow suppression, leading to a decrease in blood cell counts.

Related Terms

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