Emtricitabine/tenofovir
Emtricitabine/tenofovir (pronunciation: em-tri-SYE-ta-been/te-NOE-foe-vir) is a combination antiretroviral medication used in the treatment and prevention of HIV/AIDS.
Etymology
The name "Emtricitabine" is derived from its chemical name, 5-fluoro-1-(2R,5S)-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine. "Tenofovir" is derived from its chemical name, (R)-9-(2-phosphonylmethoxypropyl)adenine.
Usage
Emtricitabine/tenofovir is used as part of antiretroviral therapy (ART) in people with HIV. It is also used as a preventive measure, known as pre-exposure prophylaxis (PrEP), in people at high risk of contracting HIV.
Mechanism of Action
Emtricitabine and tenofovir are both nucleoside reverse transcriptase inhibitors (NRTIs). They work by blocking a process that HIV virus cells use to reproduce.
Side Effects
Common side effects include nausea, diarrhea, headache, fatigue, and dizziness. Serious side effects may include liver problems, kidney problems, and a buildup of lactic acid in the blood (lactic acidosis).
Related Terms
- Antiretroviral therapy
- Pre-exposure prophylaxis
- Nucleoside reverse transcriptase inhibitors
- Lactic acidosis
External links
- Medical encyclopedia article on Emtricitabine/tenofovir
- Wikipedia's article - Emtricitabine/tenofovir
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