Enadenotucirev
Enadenotucirev (pronounced: en-ad-en-o-tu-ci-rev) is a non-replicating adenovirus that is being studied for its potential use in cancer treatment.
Etymology
The term "Enadenotucirev" is derived from the names of the three viruses that were used to create it: Enteric Cytopathic Human Orphan virus (ECHO), Adenovirus, and Reovirus.
Description
Enadenotucirev is a type of oncolytic virus that is designed to selectively infect and kill cancer cells. It is a member of the Adenoviridae family of viruses, which are known for their ability to cause tumors in humans. Enadenotucirev is currently being studied in clinical trials for its potential use in treating various types of cancer, including colorectal cancer, ovarian cancer, and bladder cancer.
Mechanism of Action
Enadenotucirev works by selectively infecting and killing cancer cells while leaving healthy cells unharmed. It does this by exploiting the fact that cancer cells often have defects in their interferon response, which is a part of the body's natural defense against viruses. This allows the virus to replicate inside the cancer cells and cause them to burst, releasing more virus particles that can then infect other cancer cells.
Clinical Trials
Several clinical trials have been conducted to evaluate the safety and efficacy of Enadenotucirev in treating various types of cancer. These trials have shown promising results, with some patients experiencing significant reductions in tumor size and others achieving complete remission.
Related Terms
External links
- Medical encyclopedia article on Enadenotucirev
- Wikipedia's article - Enadenotucirev
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