Enamelin

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Enamelin

Enamelin (pronunciation: /ɪˈnæməlɪn/) is a protein that plays a crucial role in the mineralization of enamel, the hard, outermost layer of teeth. It is one of the key components involved in the formation and development of enamel.

Etymology

The term "enamelin" is derived from the word "enamel", which comes from the Old French esmail. The "-in" suffix is commonly used in biochemistry to denote proteins.

Function

Enamelin is secreted by ameloblasts, the cells responsible for producing enamel during the process of tooth development. It is believed to control the initiation and growth of hydroxyapatite crystals, which are the main mineral component of enamel. Mutations in the ENAM gene, which encodes the enamelin protein, can lead to amelogenesis imperfecta, a group of genetic conditions that affect the structure and appearance of enamel.

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