End-stage renal disease

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End-stage renal disease

End-stage renal disease (ESRD), also known as end-stage kidney disease (ESKD), is the final, most severe stage of chronic kidney disease (CKD).

Pronunciation

End-stage renal disease: /ɛndˈsteɪdʒ ˈriːnəl dɪˈziːz/

Etymology

The term "end-stage" refers to the final phase of a particular condition, while "renal" is derived from the Latin word "renes", meaning kidneys. "Disease" comes from the Old French "desaise", meaning lack of ease.

Definition

ESRD is characterized by a severe reduction in kidney function that is insufficient to maintain life. This stage of kidney disease typically requires dialysis or a kidney transplant for survival.

Symptoms

Symptoms of ESRD may include fatigue, nausea, vomiting, loss of appetite, weight loss, and swelling in the legs and ankles.

Causes

The most common causes of ESRD are diabetes and high blood pressure. Other causes can include glomerulonephritis, polycystic kidney disease, and certain genetic disorders.

Treatment

Treatment for ESRD typically involves either dialysis or a kidney transplant. Dialysis is a procedure that artificially cleans the blood, while a kidney transplant involves replacing the diseased kidney with a healthy one from a donor.

Related Terms

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