Eplerenone
Eplerenone
Eplerenone (pronounced as eh-pler-en-one) is a Steroidal antimineralocorticoid used primarily to treat Heart failure and Hypertension. It is a synthetic Steroid and is classified as a Selective aldosterone receptor antagonist (SARA).
Etymology
The term 'Eplerenone' is derived from the chemical name of the drug, which is 9,11α-epoxy-7α-methoxycarbonyl-3-oxo-17α-pregn-4-ene-21,17-carbolactone. The name is a combination of parts of the chemical name, with 'Epler' from 'epoxy' and 'enone' from 'carbolactone'.
Usage
Eplerenone is used to treat Congestive heart failure following a Heart attack. It is also used to treat Hypertension, particularly when other treatments have not been effective. Eplerenone works by blocking the action of the hormone Aldosterone, which can cause the body to retain salt and water, leading to raised blood pressure and strain on the heart.
Related Terms
- Aldosterone: A hormone that regulates salt and water balance in the body.
- Heart failure: A condition in which the heart is unable to pump enough blood to meet the body's needs.
- Hypertension: A condition characterized by consistently high blood pressure.
- Steroidal antimineralocorticoid: A class of drugs that block the effects of aldosterone.
- Selective aldosterone receptor antagonist (SARA): A type of drug that selectively blocks the action of aldosterone.
External links
- Medical encyclopedia article on Eplerenone
- Wikipedia's article - Eplerenone
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