Erythromelalgia

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Erythromelalgia

Erythromelalgia (pronunciation: /ɪˌrɪθroʊmɪˈældʒiə/), also known as Mitchell's disease, is a rare neurovascular disorder that is characterized by severe burning pain and reddening of the extremities. The term "erythromelalgia" is derived from the Greek words "erythros" (red), "melos" (limb), and "algos" (pain).

Symptoms

The primary symptoms of erythromelalgia are episodes of burning pain, warmth, swelling, and redness in parts of the body, particularly the hands and feet. These symptoms can be triggered by warm temperatures or physical exertion. The severity of symptoms varies among individuals and can even vary from day to day in the same individual.

Causes

The exact cause of erythromelalgia is unknown. However, it is believed to result from vasomotor abnormalities or dysfunction in the normal constriction and dilation of the caliber of certain blood vessels, leading to abnormalities of blood flow to the extremities. Some cases of erythromelalgia are associated with medical conditions such as autoimmune diseases, neurological disorders, and myeloproliferative disorders.

Diagnosis

Diagnosis of erythromelalgia is based primarily on the individual's symptoms and medical history. There are no specific laboratory tests to diagnose erythromelalgia, but certain tests may be performed to rule out other conditions.

Treatment

Treatment for erythromelalgia is aimed at relieving symptoms and can include both non-pharmacological and pharmacological methods. Non-pharmacological methods include cooling, elevation of the affected limb, and avoidance of triggers. Pharmacological treatment can include analgesics, antidepressants, and calcium channel blockers.

See also

References


External links

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