Estrone methyl ether
Estrone Methyl Ether
Estrone methyl ether (pronunciation: es-trone meth-ill ee-ther), also known as Methylestrenolone, is a synthetic, steroidal estrogen that was studied in the 1940s and 1950s but was never marketed.
Etymology
The term "Estrone" is derived from the Greek word "oistros", meaning "gadfly, breeder, sting, or sexual passion" and the suffix "-one" signifies its classification as a ketone. "Methyl ether" refers to the chemical structure of the compound, indicating that it is an ether derivative of estrone where a methyl group replaces a hydrogen atom.
Structure and Function
Estrone methyl ether is a derivative of estrone, a naturally occurring estrogen hormone. It is formed by the methylation of the hydroxyl group at the 3-position of the estrone molecule. This modification enhances the estrogenic potency of the compound compared to estrone.
Clinical Significance
Estrone methyl ether has been studied for potential therapeutic applications in conditions such as menopause, osteoporosis, and certain types of breast cancer. However, it has not been approved for medical use and is not currently marketed or available as a medication.
Related Terms
- Estrogen: A group of hormones that play an essential role in the growth and development of female sexual characteristics and reproduction.
- Methylation: A chemical process where a methyl group is added to a molecule.
- Ether: A class of organic compounds that contain an ether group.
- Hormone: Chemical messengers that are secreted directly into the blood, which carries them to organs and tissues of the body to exert their functions.
External links
- Medical encyclopedia article on Estrone methyl ether
- Wikipedia's article - Estrone methyl ether
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