From WikiMD

Information about Etodolac

Etodolac is a nonsteroidal antiinflammatory drug (NSAID) that is available by prescription only and is used long term for therapy of chronic arthritis and short term for acute pain. 

Liver safety of Etodolac

Etodolac has been linked to rare instances of clinically apparent drug induced liver disease.

Mechanism of action of Etodolac

Etodolac (e toe' doe lak) belongs to the acetic acid derivative class of NSAIDs similar to diclofenac, sulindac, ketorolac and indomethacin.  Like other NSAIDs, etodolac is a potent cyclo-oxygenase (Cox-1 and -2) inhibitor which blocks the formation of prostaglandins that are important in pain and inflammatory pathways. 

FDA approval information for Etodolac

It has analgesic as well as antipyretic and antiinflammatory activity.  Etodolac was approved in the United States in 1991 and is available by prescription only.  Currently more than 3 million prescriptions are filled yearly. 

Clinical use of Etodolac

Current indications include treatment of osteoarthritis and rheumatoid arthritis and for short term treatment of acute pain. 

Dosage and administration for Etodolac

Etodolac is available as capsules or tablets in doses of 200, 300, 400 and 500 mg generically and under the trade name Lodine.  Extended release formulations of 400, 500 and 600 mg are also available for once or twice daily dosing.  The recommended dose is 400 to 1200 mg in 2 to 4 divided doses daily, based upon response and tolerance. 

Side effects of Etodolac

Like other NSAIDs, etodolac is generally well tolerated, but side effects can include headache, dizziness, somnolence, dyspepsia, nausea, abdominal discomfort, heartburn, diarrhea, peripheral edema, pruritus and hypersensitivity reactions.

Nonsteroidal Antiinflammatory Drugs (NSAIDs)

Acetaminophen, Celecoxib, Diclofenac, Diflunisal, Etodolac, Fenoprofen, Flurbiprofen, Ibuprofen, Indomethacin, Ketoprofen, Ketorolac, Mefenamic Acid, Meloxicam, Nabumetone, Naproxen, Nimesulide, Oxaprozin, Phenylbutazone, Piroxicam, Rofecoxib, Sulindac, Tolmetin
The article on Etodolac is a stub. YOU can help Wikimd by expanding it!

Medication resources

Learn more


About WikiMD

About us: WikiMD is a free medical encyclopedia and wellnesspedia moderated by medical professionals.

Our mission: Provide up to date physician reviewed health, nutrition and wellness information for free in over 100 languages.

Join us: This article is a stub. Help improve Etodolac or others. Do not trust amateurs with your life! Join us in this effort!. Paid editors welcome.

Pubmed.png Uptodate.png Wikipedia Reddit YouTube videos
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP*

Quick links: Medicine Portal | Encyclopedia‏‎‏‎ | Gray's Anatomy‏‎ | Topics‏‎ |‏‎ Diseases‏‎ | Drugs | Wellness | Obesity‏‎ | Metabolic syndrome | Weight loss*
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer.
Link to this page: <a href="">Etodolac</a>

  • Individual results may vary for weight loss from our sponsors.