Etoricoxib

Etoricoxib

Etoricoxib (pronounced: ee-tor-ee-cox-ib) is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation in various medical conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It is also used for short-term management of moderate to severe acute pain after dental surgery.

Etymology

The name "Etoricoxib" is derived from the drug's classification as a COX-2 inhibitor. The prefix "Eto-" is a common prefix used in the names of drugs in this class, and "coxib" is a suffix used to denote COX-2 inhibitors.

Mechanism of Action

Etoricoxib works by blocking the action of an enzyme in the body called cyclooxygenase-2 (COX-2). This enzyme is involved in the production of substances in the body called prostaglandins, which cause pain and inflammation. By blocking the action of COX-2, Etoricoxib reduces the production of these prostaglandins and therefore reduces pain and inflammation.

Side Effects

Like all medicines, Etoricoxib can cause side effects, although not everybody gets them. Common side effects include headache, dizziness, stomach pain, heartburn, nausea, diarrhea, swelling of the legs and ankles (edema), high blood pressure, and allergic reactions.

Precautions

Etoricoxib should not be used by people with a history of heart disease, stroke, or high blood pressure. It should also not be used by people with a history of stomach ulcers or bleeding, or by people who are allergic to Etoricoxib or any other NSAID.

Related Terms

• Nonsteroidal anti-inflammatory drug
• Cyclooxygenase-2
• Prostaglandin
• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Gout
• Side effect
• Heart disease
• Stroke
• High blood pressure

External links

• Medical encyclopedia article on Etoricoxib
• Wikipedia's article - Etoricoxib

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