Exenatide

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Exenatide (pronunciation: /ɛksɛˈnætaɪd/) is a medication used to treat Type 2 diabetes. It is a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) also referred to as incretin mimetics.

Etymology

The term "Exenatide" is derived from the species name of the Gila monster, Heloderma suspectum, from which the active ingredient of the drug was originally isolated.

Usage

Exenatide is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes. It is not recommended for people with type 1 diabetes or for the treatment of diabetic ketoacidosis.

Mechanism of Action

Exenatide enhances glucose-dependent insulin secretion by the pancreatic beta-cell, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying.

Side Effects

Common side effects of Exenatide include nausea, vomiting, diarrhea, feeling jittery, and acid stomach. Serious side effects may include kidney problems, pancreatitis, and low blood sugar.

Related Terms

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