Fab region

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Fab region

The Fab region (pronounced: /fæb riːdʒən/) is a specific part of an antibody that binds to antigens. The term "Fab" is an acronym derived from the phrase "Fragment antigen-binding".

Etymology

The term "Fab region" is derived from the phrase "Fragment antigen-binding". This term was coined to describe the part of the antibody that binds to antigens. The "F" stands for "Fragment", the "a" for "antigen", and the "b" for "binding".

Description

The Fab region of an antibody is made up of a variable region and a constant region. The variable region is unique to each antibody and is responsible for binding to a specific antigen. The constant region, on the other hand, is the same in all antibodies of the same class and is responsible for the antibody's effector functions.

Related Terms

  • Antibody: A protein produced by the body's immune system when it detects harmful substances, called antigens.
  • Antigen: Any substance that causes your immune system to produce antibodies against it.
  • Variable region: The part of an antibody that varies from one antibody to another and binds to antigens.
  • Constant region: The part of an antibody that is the same in all antibodies of the same class and is responsible for the antibody's effector functions.

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