Fasudil
Fasudil
Fasudil (pronounced fa-SOO-dil) is a Rho kinase inhibitor used primarily in the treatment of cerebral vasospasm and to manage pulmonary hypertension. It is known for its ability to relax smooth muscle cells and has been used in the treatment of angina and other vascular disorders.
Etymology
The term "Fasudil" is derived from its chemical name, 5-isoquinolinesulfonyl homopiperazine, which is often shortened to Fasudil for ease of use in the medical community.
Usage
Fasudil is used in the treatment of cerebral vasospasm, a condition often associated with subarachnoid hemorrhage. It works by inhibiting the Rho kinase pathway, which is involved in the contraction of smooth muscle cells. By inhibiting this pathway, Fasudil can help to relax these cells and improve blood flow.
In addition to its use in treating cerebral vasospasm, Fasudil has also been used to manage pulmonary hypertension. It has been shown to improve exercise capacity and reduce pulmonary vascular resistance in patients with this condition.
Related Terms
- Rho kinase inhibitor
- Cerebral vasospasm
- Pulmonary hypertension
- Subarachnoid hemorrhage
- Smooth muscle cells
See Also
External links
- Medical encyclopedia article on Fasudil
- Wikipedia's article - Fasudil
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