Fedratinib

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Fedratinib

Fedratinib (pronunciation: /fɛˈdrætɪnɪb/) is a selective inhibitor of the Janus kinase 2 (JAK2) used for the treatment of myelofibrosis, a rare type of bone marrow cancer.

Etymology

The name "Fedratinib" is derived from its chemical structure and its function. The prefix "Fedra-" is a modification of the chemical name, and "-tinib" is a common suffix for tyrosine kinase inhibitors.

Usage

Fedratinib is used to treat adults with myelofibrosis, a rare type of bone marrow cancer. It is a type of Janus kinase 2 (JAK2) inhibitor, which works by blocking the action of JAK2, a protein that contributes to cell growth and division. By inhibiting JAK2, fedratinib can slow the growth of cancer cells.

Related Terms

  • Janus kinase 2 (JAK2) inhibitor: A type of drug that blocks the action of JAK2, a protein that contributes to cell growth and division.
  • Myelofibrosis: A serious bone marrow disorder that disrupts your body's normal production of blood cells.
  • Tyrosine kinase inhibitors: A type of drug that blocks the action of enzymes known as tyrosine kinases, which are involved in many cell functions, including cell signaling, growth, and division.

Side Effects

Common side effects of Fedratinib include nausea, vomiting, diarrhea, and fatigue. More serious side effects can include severe anemia and thrombocytopenia.

Precautions

Before starting Fedratinib treatment, patients should inform their healthcare provider about all their medical conditions, including if they have liver or kidney problems, are pregnant or planning to become pregnant, or are breastfeeding or planning to breastfeed.

External links

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