Fingolimod
Fingolimod
Fingolimod (pronounced: fin-go-li-mod) is a medication used in the treatment of multiple sclerosis (MS). It is a type of disease-modifying therapy (DMT) that works by reducing the frequency and severity of MS relapses.
Etymology
The name "Fingolimod" is derived from the compound's chemical structure. "Fin" is short for "functionalized", "go" refers to the compound's ability to modulate the immune system, and "limod" is a suffix used in the naming of immunomodulatory drugs.
Usage
Fingolimod is used to treat relapsing forms of multiple sclerosis in adults. It is not a cure for MS, but it can help to slow the progression of physical disability associated with the disease and decrease the frequency of clinical exacerbations.
Mechanism of Action
Fingolimod works by binding to sphingosine 1-phosphate receptors (S1PRs) on the surface of lymphocytes, a type of white blood cell. This prevents the lymphocytes from leaving the lymph nodes and entering the central nervous system, where they could potentially cause damage to nerve cells.
Side Effects
Common side effects of Fingolimod include headache, flu-like symptoms, diarrhea, back pain, and liver enzyme elevations. Serious side effects can include bradycardia, infections, macular edema, and respiratory effects.
Related Terms
- Multiple Sclerosis
- Sphingosine 1-phosphate receptors
- Disease-modifying therapy
- Lymphocytes
- Bradycardia
- Macular edema
External links
- Medical encyclopedia article on Fingolimod
- Wikipedia's article - Fingolimod
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski