== Information about Fluoride == Fluoride is a trace element that is concentrated in mineralized tissues such as bone and tooth enamel.
Deficiency of Fluoride
Epidemiologic surveys demonstrated a close correlation of fluoride concentrations in water with rates of dental caries, and water fluoridation began as a public health measure in the United States in the mid-1940s. Fluoride has also been shown to have a role in normal hematopoiesis, bone formation and osteoporosis and fertility and growth.
Chronic excessive fluoride intake can be associated with brown mottled teeth and skeletal abnormalities. Acute fluoride toxicity is marked by nausea, vomiting, diarrhea, abdominal pain, excess salivation and lacrimation, heart and lung abnormalities, weakness, neuropathy, convulsions, paralysis and coma.
Liver safety of Fluoride
There have been no reports of acute or chronic liver injury attributed to fluoride toxicity.
Trace Elements in Tissues and Biologic Systems