Formate

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Formate

Formate (pronounced: /ˈfɔːrmeɪt/) is a derivative of formic acid and is an important compound in biochemistry.

Etymology

The term "Formate" is derived from the Latin word forma, meaning form, and the suffix -ate, used in chemistry to denote a salt or ester of an acid.

Biochemistry

In biochemistry, formate is involved in the Formate-Hydrogenlyase pathway, where it is cleaved to carbon dioxide and hydrogen. It is also a product of the Pyruvate formate-lyase reaction, which is part of the Glycolysis pathway.

Medical Relevance

Formate is toxic and can cause metabolic acidosis, a condition characterized by an excess of acid in the body fluids. This is often seen in Methanol poisoning, where methanol is metabolically converted to formate.

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