Fospropofol

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Fospropofol

Fospropofol (pronounced fɒsˈprɒpəfɒl) is a water-soluble prodrug of propofol, a commonly used sedative and anesthetic in the medical field.

Etymology

The term "Fospropofol" is derived from its chemical structure, which includes a phosphate ester of propofol (fos- from Greek φως, meaning "light", and propofol).

Usage

Fospropofol is used as a sedative in procedures such as colonoscopy and gastroscopy. It is administered intravenously and is metabolized in the body to release propofol, providing the sedative effect.

Pharmacology

Fospropofol acts as a GABA agonist, similar to propofol, leading to sedation and anesthesia. It is metabolized by alkaline phosphatase enzymes in the body to produce propofol, phosphate, and formaldehyde. The propofol then acts on the GABA receptors to produce the sedative effect.

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