Glibenclamide

Glibenclamide

Glibenclamide (pronounced: gli-ben-cla-mide), also known as glyburide in the United States, is an antidiabetic drug in a class of medications known as sulfonylureas, closely related to sulfa drugs.

Etymology

The term "Glibenclamide" is derived from the chemical name glybenclamide, where 'gly' stands for glucose (sugar), 'ben' for benzene ring (a part of its chemical structure), and 'clamide' for the amide group present in its structure.

Usage

Glibenclamide is used to control blood sugar levels in people with type 2 diabetes mellitus who do not respond to diet, exercise, or other antidiabetic medications. It works by causing the pancreas to release insulin, which helps to lower blood sugar.

Side Effects

Common side effects of glibenclamide include hypoglycemia, nausea, heartburn, and weight gain. Severe side effects may include allergic reactions, jaundice, and low blood sodium.

Related Terms

• Antidiabetic drug
• Sulfonylureas
• Sulfa drugs
• Blood sugar
• Diabetes mellitus
• Pancreas
• Hypoglycemia
• Allergic reactions
• Jaundice
• Low blood sodium

External links

• Medical encyclopedia article on Glibenclamide
• Wikipedia's article - Glibenclamide

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