Glicaramide
Glicaramide
Glicaramide (pronunciation: gli-ca-ra-mide) is a hypoglycemic agent used in the treatment of diabetes mellitus. It belongs to the sulfonylurea class of medications, which work by stimulating the release of insulin from the pancreas.
Etymology
The term "Glicaramide" is derived from the words "glycemia" referring to the presence of glucose in the blood, and "amide" which is a common suffix in organic chemistry indicating the presence of an amide group in the molecule.
Usage
Glicaramide is used to control high blood sugar in people with type 2 diabetes mellitus. It is used when diet and exercise alone does not result in the adequate control of blood sugar.
Mechanism of Action
Glicaramide works by stimulating the release of your body's natural insulin. It does this by binding to and blocking the ATP-sensitive potassium channels in the pancreatic beta cells. This depolarizes the cell membrane and opens calcium channels, leading to an influx of calcium. This triggers the release of insulin.
Related Terms
- Sulfonylurea
- Insulin
- Diabetes mellitus
- Hypoglycemic agent
- Pancreas
- ATP-sensitive potassium channels
- Beta cells
External links
- Medical encyclopedia article on Glicaramide
- Wikipedia's article - Glicaramide
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