Halofantrine

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Halofantrine

Halofantrine (pronounced: ha-lo-fan-trine) is a drug used in the treatment of malaria. It is a phenanthrene methanol, chemically related to the antimalarial agents quinine and quinidine.

Etymology

The term "Halofantrine" is derived from the chemical structure of the drug, which includes a halogenated phenanthrene core and an amino alcohol side chain. The "-fantrine" suffix is common to a group of related antimalarial drugs.

Usage

Halofantrine is used to treat malaria caused by Plasmodium falciparum and Plasmodium vivax. It is not typically used as a first-line treatment, but rather reserved for cases where other treatments have failed or are not suitable.

Mechanism of Action

Halofantrine works by inhibiting the growth of the parasite's DNA and RNA, preventing it from reproducing and spreading.

Side Effects

Common side effects of Halofantrine include nausea, vomiting, diarrhea, abdominal pain, and dizziness. In rare cases, it can cause serious heart problems, so it should be used with caution in patients with known heart conditions.

Related Terms

External links

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