Haplotype
Haplotype
Haplotype (/ˈhæplətaɪp/; from the Greek: ἁπλοῦς, haplous, "single, simple") is a group of genes within an organism that was inherited together from a single parent. The term is derived from the combination of haploid and genotype.
Definition
A Haplotype is a set of DNA variations, or polymorphisms, that tend to be inherited together. It can refer to a combination of alleles or to a set of single nucleotide polymorphisms (SNPs) found on the same chromosome.
Etymology
The term haplotype is derived from the Greek words haploûs, meaning "single" or "simple", and typos, meaning "mark" or "general form". It was first used in this context in the early 1960s.
Related Terms
- Genotype: The genetic makeup of an organism or group of organisms with reference to a single trait, set of traits, or an entire complex of traits.
- Phenotype: The observable physical or biochemical characteristics of an organism, as determined by both genetic makeup and environmental influences.
- Allele: One of two or more alternative forms of a gene that arise by mutation and are found at the same place on a chromosome.
- Chromosome: A threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes.
- Polymorphism (biology): The occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
See Also
External links
- Medical encyclopedia article on Haplotype
- Wikipedia's article - Haplotype
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