Humanized

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Humanized

Humanized (/hjuːˈmaɪ.zəd/), from the Latin humanus meaning human, is a term often used in the field of medicine and biotechnology to refer to the process of modifying non-human substances, such as antibodies, to make them more similar to those found in humans. This process is typically done to reduce the risk of immune response when these substances are used in human treatments.

Etymology

The term "humanized" is derived from the Latin word humanus, which means human. It is used to describe the process of making something more human-like or suitable for use in humans. In the context of medicine and biotechnology, this usually refers to the modification of non-human substances to make them more similar to those found in humans.

Related Terms

  • Monoclonal Antibodies: These are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope.
  • Chimeric Antibodies: These are antibodies that are composed of human and non-human portions, usually mouse, designed to interact with both human and non-human cells.
  • Fully Human Antibodies: These are antibodies that are completely derived from human sources or produced in vitro using human immunoglobulin gene libraries.
  • Immune Response: This is a reaction that occurs within an organism for the purpose of defending against foreign invaders. These invaders include a wide variety of substances, such as harmful bacteria, viruses, and cancer cells.
  • Biotechnology: This is a broad area of biology, involving the use of living systems and organisms to develop or make products.

See Also

External links

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