Hypotonic-hyporesponsive episode

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Hypotonic-Hyporesponsive Episode

Hypotonic-hyporesponsive episode (HHE) is a sudden and temporary condition that typically occurs within 48 hours after receiving a vaccination. The condition is characterized by a sudden loss of muscle tone (Hypotonia), unresponsiveness, and changes in skin color.

Pronunciation

The term is pronounced as hy-po-ton-ic hy-po-re-spon-sive ep-i-sode.

Etymology

The term is derived from the Greek words 'hypo' meaning 'under' or 'less than normal', 'tonic' referring to 'tone' or 'tension', and 'episode' meaning 'a happening'.

Symptoms

The main symptoms of an HHE include sudden loss of muscle tone (Hypotonia), unresponsiveness to stimuli, and changes in skin color. The affected individual may appear pale or blue (Cyanosis), and may be limp or unresponsive.

Causes

HHE is most commonly associated with the administration of whole-cell pertussis vaccines, but it can also occur after the administration of other vaccines. The exact cause of HHE is not known, but it is thought to be related to an abnormal response to the vaccine.

Treatment

Treatment for HHE is supportive and involves monitoring the individual until they recover. In most cases, the episode is self-limiting and the individual recovers without any long-term effects.

Related Terms

See Also

External links

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