From WikiMD

IQ motif and Sec7 domain 2 is a protein that in humans is encoded by the IQSEC2 gene.[1][2]


The IQSEC2 gene encodes a guanine nucleotide exchange factor for the ARF family of GTP-binding proteins (see for example ARF1).[3]

Clinical significance

It is associated with X-Linked mental retardation 1.[3]


  1. 3.0 3.1

Further reading

Template:GTP-binding protein regulators


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