Ichthyosis vulgaris

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Ichthyosis vulgaris

Ichthyosis vulgaris (pronounced ik-thee-OH-sis vul-GAIR-is), also known as common ichthyosis or fish scale disease, is a skin condition characterized by dry, scaly skin. It is the most common form of ichthyosis, affecting around 1 in 250 people.

Etymology

The term "ichthyosis" is derived from the Ancient Greek ιχθύς (ichthys), meaning 'fish'. The suffix "-osis" denotes a condition or disease, and "vulgaris" is Latin for 'common'. Thus, the term literally translates to 'common fish disease'.

Symptoms

The primary symptom of ichthyosis vulgaris is dry, scaly skin that resembles fish scales. Other symptoms may include itching (pruritus), redness (erythema), and skin thickening (hyperkeratosis). The severity of symptoms can vary widely among individuals.

Causes

Ichthyosis vulgaris is typically caused by a genetic mutation in the FLG gene, which is responsible for the production of a protein called filaggrin. Filaggrin plays a crucial role in the skin's ability to retain moisture. A deficiency in filaggrin can lead to dry, scaly skin.

Treatment

While there is no cure for ichthyosis vulgaris, treatments can help manage symptoms. These may include the use of moisturizers and keratolytic agents, which help to soften and remove scales. In severe cases, retinoids may be prescribed.

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