Immunoglobulin E
Immunoglobulin E
Immunoglobulin E (pronounced /ˌɪmjʊnoʊˈɡlɒbjʊlɪn ˈiː/), often abbreviated as IgE, is a type of antibody (or immunoglobulin (Ig) that has only been found in mammals. It plays an essential role in the body's immune system against allergens.
Etymology
The term "Immunoglobulin E" is derived from the word "immune", referring to the body's defense system, and "globulin", which is a broad term for a class of proteins in the blood, including antibodies like IgE.
Function
IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE may also be important during immune defense against certain protozoan parasites such as Plasmodium falciparum.
IgE also plays a pivotal role in responses to allergens, such as: dust mites, pollen, and food allergies.
Related Terms
- Antibody: A protein produced by the body's immune system when it detects harmful substances.
- Allergen: A type of antigen that produces an abnormally vigorous immune response.
- Immune System: The body's defense against infectious organisms and other invaders.
- Parasites: Organisms that live on or in a host organism and gets its food from or at the expense of its host.
External links
- Medical encyclopedia article on Immunoglobulin E
- Wikipedia's article - Immunoglobulin E
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